Laser cleaning is a new type of laser application technology in which the high-powered lasers are used to irradiate the surface of substrates based on the algorithm of interaction between the laser and the substance, destroying the bonding force between the substrate and the stain. So that, the stain can be separated from the surface of a substrate. Recently, with the development of laser technology, the application range of laser cleaning has continued to expand, and the new researches such as particle cleaning, mold cleaning, and transportation cleaning, etc. have been carried out, but there are still some disadvantages, such as expensive equipment, long test time, etc. In order to understand the research status of laser cleaning in recent years, the laser cleaning mechanism, application field, development status and existing problems have been briefly described, and the advantages of the new laser composite cleaning technology have also been mentioned in green manufacturing and its development potential.