Chinese Journal of Lasers, Volume. 41, Issue 10, 1004001(2014)

Compact Optical-Resolution Photoacoustic Microscopy System Based on a Pulsed Laser Diode

Zeng Lüming1、*, Liu Guodong1, Yang Diwu2, Ji Xuanrong3, Huang Zhen1, and Dong Jian1
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  • 1[in Chinese]
  • 2[in Chinese]
  • 3[in Chinese]
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    A compact optical-resolution photoacoustic microscopy system is designed with a pulsed laser diode, which has the properties of being low cost, small size, robust and high repetition frequency. Typical photoacoustic images of carbon fiber and blood vessel phantoms are reconstructed clearly. During the experiments, the pulsed laser diode excitation is droved to implement C-mode scanning excitation with three-dimensional translation stage, and the excited photoacoustic signal is captured by a 1-3 composite ultra-bandwidth ultrasonic transducer. The photoacoustic signal-to-noise ratio is recorded of approximate 11 dB, and the lateral resolution of the current system is improved up to 1.5 μm from 500 μm of the first-generation system. The experimental results demonstrate that the proposal method has the potential to be developed as a configuration of inexpensive, real-time, portable, and high-resolution photoacoustic microscopy technique.

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    Zeng Lüming, Liu Guodong, Yang Diwu, Ji Xuanrong, Huang Zhen, Dong Jian. Compact Optical-Resolution Photoacoustic Microscopy System Based on a Pulsed Laser Diode[J]. Chinese Journal of Lasers, 2014, 41(10): 1004001

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    Paper Information

    Category: biomedical photonics and laser medicine

    Received: Apr. 8, 2014

    Accepted: --

    Published Online: Aug. 12, 2014

    The Author Email: Zeng Lüming (zenglvming@163.com)

    DOI:10.3788/cjl201441.1004001

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