Optical glasses with defocus design, which can reduce eye axial length growth and control the progression of myopia, is a common optical correction method for children and adolescents with myopia. In order to further standardize the design of optical defocus lens and ensure the myopic control effect that the lens might achieve, Shanghai Eye Disease Prevention and Treatment Center(Shanghai Eye Hospital), Shanghai Glasses Industry Association and Shanghai Medical Association Optometry Branch have put forward this guideline together as reference for optical industry practitioners, ophthalmologists and optometrist.