The cylindrical lens type glasses-free 3D display system has developed rapidly in various fields in recent years. In order to further solve the problem of cylindrical lens type naked eye 3D crosstalk, a method is proposed to reduce the crosstalk between adjacent viewpoints of cylindrical lens grating autostereoscopic displays by shifting the pixel position on the LCD image panel, reducing the pixel interval and adjusting the tilt angle of the cylindrical lens. The causes of crosstalk for the dual-view cylindrical lens type naked eye 3D display system were analyzed.Paramefers such as the thickness,pitch,focal length and carvature radius of cylindrical lens were calculated. The relationship between pixel position, cylindrical Lens tilt angle,pixel interval, crosstalk area and moive thickness of LCD image panel is examined. The relationship between the thickness of the moiré fringe reduces the maximum crosstalk at the edge of the viewing zone while ensuring the thickness of the moiré fringe remains unchanged. The above method is simulated by Lighttools software, and the local area with the number of pixels of 120×60 is simulated. The results show that the maximum crosstalk at the edge of the viewing zone before and after the improvement is reduced from 50% to 30%, and the crosstalk at the best view point is reduced from 0.93% to 0.32%, and the best view point area is extended by ±15mm, which is of reference significance for reducing cylindrical lens-type naked eye 3D crosstalk.