Two-dimensional (2D) MXene nanomaterials have shown great promise for electronic devices, attributed to their metal-resembling conductivity and abundant surface functional groups. However, the utilization of intrinsic property of MXene in memristors remains challenging due to its free electron conducting behavior rather than semiconducting property. Here, a N-fused perylenediimide organic semiconductor (CBIN) with conjugated skeleton and heteroatoms (O, S, N) is designed to successfully actuate the surface modification of MXene. The organic CBIN-decorated MXene demonstrates remarkable bipolar memristive properties, such as low threshold voltages of approximate ±1.4 V, exalted retention time exceeding 10⁴ s, and outstanding environmental stability even after exposure to ultraviolet and x-ray irradiations. Furthermore, the CBIN-MXene hybrid memristive device can mimic synaptic plasticity and holds potential for information encoding as quick response codes and image recognition processing. This study provides efficient guidelines for implementing MXene-based memristors by organic semiconductor modulation and opens up possibilities of extending their functionalities into information encryption and neuromorphic computing applications.