Objective: In order to analyse the safe and security of CO₂ Laser with silver halide optial fibers which made by Shanghai in stiute of Ceramics, Academia. Methods: 128 cases which involving skin, mouth, cervix, sig-moid colon, rectum and anal canal were treated by CO2 Laser with silver Halide optical fibers. The tissue were vapoured and cabonized by CO2 Laser. Results: After a certain period of time's follow-up and obervation. the results were found with satisfactory, which assures us that this kind of treatment has the feature of stable output officiency, reliable safety easy to handle and it meets the require ments of a successful obervation. During the 3 month' s followup and obervation, the recovery rate is up to 97%. Couclusion: The CO2 laser with silver halide optial fibers has the best quality. It meets the require meat of successful iperation. It is suitable for the therapy of endocavity in the end.