The electron probe micro-analyzer (EPMA) technology is used to analyze and study various forms of platinum (Pt) particle inclusions in continuous-smelted Nd∶glass before and after intense laser irradiation. After intense laser irradiation, platinum particle inclusions exhibit three typical EPMA morphology. Their forms come from the joint result of the thermal stress and vapor pressure caused by platinum particles absorbing laser energy. The thermodynamic properties of Nd∶glass also have an effect on the morphology. The phenomenon of Pt-Zr-Sn being co-wrapped is found by comparing the EPMA distribution characteristics of zirconium and stannum impurity inclusions.