The deposited Ti600 titanium alloy for internal combustion engine was prepared by laser rapid prototyping. The microstructure of titanium alloy in several orientations (laser scanning direction 45°, scanning direction, and deposition direction) was characterized by relevant instruments, and its static compression characteristics at room temperature were tested by MTS universal tensile machine. The results show the β phase grows epitaxially with high temperature gradient in the deposition direction, and isometric structure is produced with size approaching 400 μm. The crystal structure of dense hexagonal type is formed in all samples. At the 45° angle direction, samples present (101) preferred orientation. Many dimples and tearing edges are formed at the fracture of each orientation specimen, which show ductile fracture. According to the dimple size, the largest one is at deposition direction, follows by scanning direction and 45°. The 45° oriented samples show a higher strength with yield strength close to 890 MPa, and fracture strength being 980 MPa. The strength of samples at deposition direction and the scanning direction are basically the same. The samples (101) at 45°orientation reduce the grain coordination ability during the deformation stage and inhibit the deformation process so as to produce the highest grain strength and low plasticity.