Co-based alloy coating is prepared on the sealing surface of the seat made by 410-stainless steel. Effects of different Co-based powder and different process parameters and the subsequent heat treatment on the variation of formability and properties of the cladding coatings are analyzed by metallographic analysis, hardness testing and scanning electron microscopy. The result shows that the powder prepared by A and C has has good moldability, and with the increase of scanning speed, the width of the cladding layer decreases, the hardness increases, the cladding cracks tend to increase. The effects of the heat treatment on the hardness of the cladding coating is not obvious, but it can It can significantly reduce the hardness of the HAZ. The optimum technology is laser power 3.5 kW, scanning speed 100～150 mm/min, the mixtured powder of A and C was prepared for coating by laser cladding, then take the tempering on the cladding coating. We can get the cladding coating meet the requirement on the 410-stainless steel.