Laser lipolysis technology is in a relatively preliminary stage, and the current research lacks the parameter information applicable to human body. In the process of laser lipid dissolving, temperature, as an important quantity, is difficult to be monitored in real time. In this paper, the effects of 1 064 nm Nd: YAG continuous laser on the temperature rise of pig fat were studied through a series of experiments in combination with the multi-channel grating optical fiber temperature measurement system. The experimental scheme of continuous fat dissolution was designed and verified. Results show that the transmissive power of 1 064 nm Nd: YAG laser in fat is less than 2 mm. The heat distribution generated by the photothermal effect is also concentrated in the radial and axial tissues within 5 mm. In addition, the temperature distribution is closely related to the power density and irradiation time of the fat laser. After the irradiation temperature reaches 35 ℃, the parameters that keep the temperature within the safe range within a certain period of time are: power density 27.08 W/cm2, irradiation time 16 s, natural cooling 9 s; power density 40.62 W/cm2, irradiation time 9 s, natural cooling 9 s.