Based on the needs of processing generation and characteristics in the automatic processing line of LCD substrate glass ，the enterprises have selected their own appropriate end face processing technologies， continuously upgraded and improved production capacity.Systematically discussed the different classifications of end face processing technologies applicable to the field of substrate glass processing，the effects of key materials on processing quality，and the research and exploration of the influences of adjustment of processing parameters on processing quality. As a result，in during the grinding process，the grinding wheel serves as a key material， and the diamond particle size plays a decisive role in the roughness of the finished substrates.In addition，the adjustment of processing parameters and the resolution of defect problems in production also have significant effects on processing quality.