In order to improve the image quality of the space TDI CCD remote sensing cameras, the method to set optimally of TDI CCD integration stages and gains was proposed. The dependence of the Signal to Noise Ratio(SNR) and Modulation Transfer Function(MTF) on the integnation stages was discussed.Then, it points out that increasing integration stages can resolve the lack of exposure light energy and improve SNR,but it causes the image MTF reduced. However,increasing gains can also resolve the problem of lack of exposure light,and it makes the SNR and the imaging MTF unchanged. These results means that the set of the SNR and imaging MTF can improve the image quality. By using the SNR×MTF as the optimal goal, this paper optimizes the integration stage and the gain. Numerical calculation result shows that when the pitch speed of satellite is 0.005°/s and the exposure is 1/66 of saturation,the high quality image can be obtained in the integration stage to be 44 and the gain to be 1.5.