The exploration of strong terahertz radiation sources plays a crucial role in the development of terahertz technology. Femtosecond laser-induced strong terahertz emission in a liquid line of n-octanol solution is experimentally confirmed using an alcohol solution as a terahertz excitation medium. Under the same laser excitation conditions, the terahertz radiation generated in the n-octanol solution is 3.5 times stronger than in liquid water. The terahertz emission angle in n-octanol solution is investigated, and it is shown that the intensity of the terahertz radiation generated in n-octanol solution is maximum at a detection angle of 90°, while the terahertz emission angle ranges from 45° to 135°. In addition, quantum chemical calculations on alcohols are performed to explain the physical mechanism of strong terahertz generation in alcohol solutions. The results show that the terahertz radiation generated in alcohol solutions is negatively correlated with its band gap, surface electrostatic potential, dielectric constant, and MPI polarity index.