To analyze the stress conditions of bridge deck panels with different stiffener forms in steel box girders, the software ANSYS is used to establish a comprehensive model and a spatial shell local model for a single box double-chamber continuous steel box girder with a span of（32+40+32）m．The effects of the main girder system and bridge deck system are obtained, and a comparative analysis is conducted on the structural effects of commonly used open section（inverted T-shaped）stiffeners and closed section（U-shaped）stiffeners in bridge deck panels．The results indicate that：1）The overall model reveals that the stress situation of the main girder system in the steel box girder, under basic combination effects and fatigue load effects, shows that the displacements and stresses of the bridge deck panels with inverted T-shaped stiffeners and U-shaped stiffeners are quite similar. 2）Under local vehicle load, the longitudinal and transverse stresses of the inverted T-shaped stiffener bridge deck panel are more than twice those of the U-shaped stiffener bridge deck panel; the maximum longitudinal stress of the inverted T-shaped stiffener is greater than that of the U-shaped stiffener, while the vertical shear stress is smaller than that of the U-shaped stiffener and is lower than that of the bridge deck panel; the transverse and vertical stresses of the U-shaped stiffener steel box girder web are significantly increased compared to the inverted T-shaped stiffener, with a maximum increase of about 3.5 times．In design, adjustments should be made to the stiffness of the longitudinal and transverse stiffeners to ensure balanced stress in all components; the local deformation trends of the bridge deck panels in the inverted T-shaped and U-shaped stiffener models are similar, but the local deformation of the bridge deck panel under the inverted T-shaped stiffener model is larger than that of the U-shaped stiffener model, approximately 1.2 times the displacement of the latter．