To apply infrared imaging detection technology for gas leakage in petrochemical enterprises, experimental research has been conducted on common gases such as methane and ethylene. The influencing factors, such as gas infrared absorption characteristics, gas concentration, background temperature, and detector sensitivity, were systematically studied, and the characteristics of gas infrared thermal imaging technology and infrared spectral imaging technology were analyzed. Based on the experimental research and analysis, some suggestions have been put forward for the application of infrared imaging detection technology for gas leakage in petrochemical enterprises.