In order to realize the optimal route planning and promote the energy-saving and loss reduction of overhead ground wire, the energy-saving grounding technology of overhead ground wire of transmission line based on multi-objective evolutionary algorithm is studied. Aiming at the lowest risk of geological disasters and the highest operation safety factor of overhead ground wire route, an optimization model of overhead ground wire route of transmission line is established. The multi-objective evolutionary algorithm is used to solve the model and obtain the route optimization scheme. The energy-saving grounding technology of single circuit or multi circuit overhead ground wire is selected according to the actual geological conditions. The experimental results show that the proposed technology can obtain the optimization scheme of overhead ground wire route of transmission line in line with the objective function and constraints. The energy-saving grounding mode is selected as two overhead ground wires of single circuit line, the pitch of each section of overhead ground wire is 6.4 km, and the grounding point is selected at the middle point of each section of ground wire. Compared with the previous year, the power loss of this grounding mode is reduced by 60% ~ 69%, and the energy-saving effect is outstanding.