It is reported for the first times that prostate samples of rabbits are irradiated by a Xecl excimer laser (308nm).The ablation effects of the prostates of the rabbits are observed with different laser pulse repetition rates and two lasing media. The damase threshold of 400 mJ/ cm2 is measured. It is shown that the excimer laser has the characteristics of good ablation effect, light damage for surrounding tissues and easy control,thus presenting a practical clinical value.