Rumen simulation is an important technique to study animal nutrition and metabolism in vitro, which is mainly divided into batch culture method and continuous culture method. This paper reviews the classification of artificial rumen simulation technology and its research and application in the field of animal nutrition at home and abroad in recent years, such as evaluation of feed nutritional value, evaluation of different feed combination effects, evaluation of rumen fermentation characteristics of feed additives and etc. aiming to provide references for related research.