Laser & Optoelectronics Progress, Volume. 62, Issue 18, 1817021(2025)

Brillouin Scattering Elastic Imaging for Lens in ex-vivo Porcine Eye (Invited)

Lei Wang1,2, Mingxuan Liu1,2, Hao Huang1,2, Jin Xu1,2, Xingdao He1,2、*, and Jiulin Shi1,2、**
Author Affiliations
  • 1Key Laboratory for Optoelectronic Information Perception and Instrumentation of Jiangxi Province, Nanchang Hangkong University, Nanchang 330063, Jiangxi , China
  • 2Key Laboratory of Nondestructive Testing (Ministry of Education), Nanchang Hangkong University, Nanchang 330063, Jiangxi , China
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    Spontaneous Brillouin scattering detection system based on a dual-stage virtual imaging phase array (VIPA) spectrometer is proposed for elastic imaging of lens capsule and lens section of ex-vivo porcine eye. Results show that the Brillouin longitudinal elastic modulus of the porcine eye lens capsule is approximately 2.90 GPa at the equator and 2.84 GPa at the detect edge, and shows a gradual decrease from the equator toward the posterior pole. The Brillouin longitudinal elastic modulus of the porcine eye lens nucleus is about 3.72 GPa and is distributed in a plateau region at the center of the nucleus, it is about 3.32 GPa at the detect edge, and shows a gradual decrease from the lens nucleus to the surrounding cortical layers. Using Brillouin microscope to characterize the biomechanical properties of porcine eye lens, which is not only important for understanding the process of human eye regulation, but also can provide technical support for the diagnosis and treatment of human hyperopia.

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    Lei Wang, Mingxuan Liu, Hao Huang, Jin Xu, Xingdao He, Jiulin Shi. Brillouin Scattering Elastic Imaging for Lens in ex-vivo Porcine Eye (Invited)[J]. Laser & Optoelectronics Progress, 2025, 62(18): 1817021

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Jul. 23, 2025

    Accepted: Jul. 31, 2025

    Published Online: Sep. 11, 2025

    The Author Email: Xingdao He (xingdaohe@126.com), Jiulin Shi (jiulinshi@126.com)

    DOI:10.3788/LOP251750

    CSTR:32186.14.LOP251750

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