Clinical nursing of ophthalmology and optometry is a highly specialized and interdisciplinary medical subject. The establishment and optimization of its teaching evaluation system is crucial for improving teaching quality and cultivating qualified professionals in the field of ophthalmology and optometry. By combining literature review and empirical research, this paper explored the necessity of establishing a teaching evaluation system for clinical nursing of ophthalmology and optometry, analyzed the problems existing in the current evaluation system, and proposed optimization strategies. In order to establish and optimize the teaching evaluation system of optometry clinical nursing, diversified evaluation methods must be adopted in teaching evaluation, and the application and feedback of evaluation results should be strengthened. Only in this way can we obtain a scientific and perfect teaching evaluation effect. This work was expected to provide reference for clinical nursing of ophthalmology and optometry education, promote the perfection and development of the discipline, and enhance the status and influence of the discipline.