Ni-based alloy reinforced coating was prepared on the surface of 5CrNiMo steel, and the effects of scanning speed(6、8、10 mm/s)on the microstructure and properties of the cladding were analyzed. X-ray diffractometer、scanning electron microscope、energy spectrum analyzer、micro hardness tester and friction and abrasion tester were used to analyze and test the phase composition、microstructure、microhardness and wear resistance of the cladding The results show that the cladding layer is mainly composed of CrB2, Cr3B2, Cr7C3 and γ-Ni phases. With the increase of the scanning speed, the structure of the cladding layer is refined, the distribution is uniform, the micro hardness is increased, the amount of wear is reduced, and the friction coefficient is reduced. Laser cladding technology can successfully prepare Ni-based alloy reinforced coatings on the surface of 5CrNiMo. Choosing a suitable scanning speed can improve the microstructure of the cladding layer. When the tracing speed is 10 mm/s, the cladding layer has fine grains, dense and uniform structure distribution, and abrasion resistance and microhardness are significantly improved.