The wired communication mode of industrial bridge crane will increase the labor cost, and the later maintenance is relatively difficult. Therefore, a design scheme of laser wireless communication system based on PLC is proposed. The hardware part of the system is composed of laser sensor information acquisition layer, information transmission layer and information fusion output layer. The laser sensor obtains data information, completes transmission through ZigBee communication technology, and realizes data fusion in the information fusion module. The system software consists of PLC module, laser sensor routing node module and information fusion module. PLC module receives external signals and determines signal status information. The routing node module records the address information of the sensor data. By using BP neural network algorithm to remove redundant data and compress the amount of data, the sensor information can get ideal fusion results. Through the system performance test, the results show that the proposed system has low communication error rate, low communication delay and communication overhead, which can realize efficient and fast laser communication transmission.