The miniaturization is the current development trend of pulsed laser proximity fuze. In addition to considering the impact of structural overload, the problem of space electromagnetic interference caused by the miniaturization of the structure can not be ignored. Based on the miniaturization background, a theoretical model of pulsed laser emission system is established, and the instantaneous discharge peripheral radiation is simulated by Comsol software. Analyzing the electromagnetic radiation interference on the detection system caused by the pulse current of the emission system, it proposes the anti-electromagnetic radiation interference measures based on the electromagnetic shielding mechanism. The experimental and simulation results show that the instantaneous discharge of the laser emission system will produce great electromagnetic radiation interference effectively suppressed by the 45 steel combined shielding mechanism.