Objective:For inquire into the clinical effect of tattoo treated by Q - Switched Nd: YAG Laser. Methods:We treated patients of Various tattoo by Q - Switched Nd:YAG Laser. The Q - Switched Nd:YAG energy density was 5 - 12J/pulse, pulse repetition rate 1,2,5,10Hz, beam spot sizes 2,3,4,6mm. For pigmentary disease involving deep layer tissue need treatment for several times. The time of interval treatment was about 3 months. Results: In all 150 cases of tattoo. Cure rate in the first session was 30%. The frequency of treatment effect was up to 100%. Conclusion:It is a securing method having good cured results with no sear and less pain.