By doubling the frequency of two laser beams whose wavelength is 1064 nm and 1320 nm, 532 nm and 660 nm laser are obtained, separately. The fiber with 300 μm diameter is used to transfer those laser beams to body cavity for interposition treatment The result shows that KTP/YAG 532 run and 660 nm laser is better for interposition treatment than the YAG 1064 nm and 1320 nm.