A high-dynamic image generation algorithm based on multi-factor fusion of long and short exposures for the actual use scenarios of the camera is proposed in this paper，which solves the problem of narrow dynamic range in the actual shooting process of the camera and improves the measurement effect of the camera. Starting from the image data of long exposure and short exposure，the algorithm comprehensively considers multiple weight factors such as gradient，saturation，brightness，etc.，and generates and fuses a high dynamic image based on multi-scale sampling，which effectively overcomes the problem of excessive dynamic range and generates a more realistic and detailed image. Experimental results show that compared with the traditional algorithm，the proposed algorithm can effectively reduce noise and achieve better imaging results while maintaining image details，and the imaging effect can be improved by about 20%.