A laser diode (LD) end-pumped Nd∶YVO4 three-wavelength laser is reported by BIBO intracavity second harmonic generation(SHG) and sum-frequency mixing (SFM) at the same time. Through the two different transitions(1064 nm and 1084 nm) of Nd∶YVO4 crystal as fundamental waves and a nonlinear crystal BIBO with 1.5 mm-thick and type-I phase matching cut for SHG on 1064 nm, a three-wavelength laser with two doubling waves (532 nm and 542 nm) and one SFM wave (537 nm ) is obtained by adjusting the phase matching factor, nonlinear conversion efficiency, of the three nonlinear frequency conversion processes (1064 nm and 1084 nm SHG respectively, 1064 nm and 1084 nm SFM). The experimental results show that SGH and SFM of nonlinear crystal with little phase accepted angle is an efficient way to realize multi-wavelength laser when two fundamental waves with a little interval wavelength.