Microwave measurement is an important part of microwave engineering. In order to cultivate students’ practical and engineering application abilities in microwave measurement, an “opening blind box” series of inquiry-validation experiments is designed for the course of Microwave Technology. The series experiments of “opening blind box” microwave measurement focus on measuring standing wave ratio, load impedance, two-port network S-parameters, etc. In each measurement experiment, multiple measurement objects are set without providing basic indexes, and microwave device are measured through “open blind box” method, which increases the uncertainty of the experimental results. At the same time, “hidden items” are set in the measurement objects to exercise student’s microwave engineering practical ability and problem-solving ability, which establishes a technical foundation for students to further design microwave components.