Seven cultivation patterns of ground semi-soil cover, ground leaning, multi-tiered shelf, horizontal suspending, wall suspending, shelf container orientation and shelf orientation were used to cultivate Lentinus edodes. The facility cost, management cost, yield and quality of fresh mushroom, biological efficiency and economic benefits were compared and analyzed. The results showed that among the vertical cultivation patterns in greenhouses with same area, the shelf container orientation and shelf orientation patterns showed the maximum amount of artificial bed-log in single season, both of which were 6 500 rods. Based on the service life of the facility is 10 years and the cultivation season is 2 seasons per year, the average facility cost is 0.24 yuan per rod and 0.23 yuan per rod respectively. The average management costs amounted to 0.35 yuan per rod and 0.48 yuan per rod respectively. The biological efficiency was 91.26% and 93.23%, and the proportion of high quality mushrooms was 89.34% and 91.25% respectively. The average profit calculated by market survey was 4. 43 yuan per rod and 4. 55 yuan per rod, respectively. The return on investment (ROI) is high, 92.74% and 99.96% respectively, and the return on investment can be almost realized in single season cultivation. In non-vertical cultivation pattern, the ROI of the ground semi-soil cover pattern and ground leaning pattern is at the level of 70%, which is suitable for small and medium-sized cultivators with low investment risk. For the standardization and large-scale production of L. edodes, the cultivation pattern of L. edodes with shelf cortainer orientation or shelf orientation can better meet the market requirements.