ObjectiveTo explore the risk factors for poor prognosis in patients with type 2 diabetes mellitus(T2DM) complicated by coronary heart disease (CHD).MethodsA retrospective analysis was conducted on the clinical data of 117 patients with T2DM complicating CHD. The patients were divided into a poor prognosis group(67 cases) and a good prognosis group (50 cases) based on their clinical outcomes. Baseline data, number of diseased coronary arteries, laboratory test indicators and other data were collected, and compared between the two groups. Binary Logistic regression analysis was used to identify the risk factors for poor prognosis.ResultsThe levels of glycated hemoglobin (HbA1c), the proportion of patients with multi-vessel coronary artery disease, as well as the prevalence of hypertension and hyperlipidemia were all significantly higher in the poor prognosis group than those in the good prognosis group (all P< 0.01). Logistic regression analysis showed that HbA1c, multi-vessel disease, hypertension, and hyperlipidemia were independent risk factors for poor prognosis in patients with T2DM and CHD (all P< 0.05).ConclusionActively controlling blood glucose, blood pressure and lipid levels, as well as optimizing coronary artery revascularization strategies are of significant importance for improving the prognosis of patients with T2DM and CHD.