Objective:To evaluate the effectiveness of selective laser photocoagulation treatment for the peripheral retinal breaks. Methods:44 eyes in 38 patients of peripheral retinal breaks accompanied with eye flashing or/and vitreous floaters were included in this study, all the eyes were precluded visual defect and extensive retinal degeneration over 2 quadrants. Double or triple rows of argon laser burns were applied around or behind the posterior rim of the lesion if it was too peripheral. Results: During the mean follow-up period of 16 months, no change in visual acuity and visual field was noted after treatment as compared with those of before treatment in 43 eyes, and no complication was observed in these eyes. The subretinal fluid progressed in 1 eye so the cryopexy and scleral buckling surgery were intervened. Conlusion: Laser photocoagulation is an efficacious method to treat the peripheral retinal breaks and degenerations . Complications could be reduced to a minimum in selective patients.