The matching between industrial agglomeration and spatial resources is related to the efficient utilization of resources. This study employs ArcGIS tools with 100 m×100 m grid cells, combined with methods such as enterprise value evaluation system, location entropy index, spatial production intensity index, and coupling coordination degree model. By analyzing productive industry agglomeration and spatial utilization intensity, it investigates the alignment between industrial agglomeration and spatial resources along with influencing factors. The research finds that the business scale of productive service industries and manufacturing enterprises in Liuhe District has increased significantly, and advanced service industries and manufacturing have become the industrial focus. The high agglomeration space of productive service industry is relatively concentrated, while the high agglomeration space of productive manufacturing industry is relatively dispersed. The collaborative agglomeration of the two industries is mainly at level Ⅱ-Ⅲ, and the intensity of industrial spatial development is mainly low to relatively low. Among them, high-intensity spaces mainly expand outward from the urban area as the center; The agglomeration spatial matching and collaborative agglomeration spatial matching of productive service industries show an upward trend at the intermediate level or above in industrial agglomeration spatial matching. And industrial agglomeration spatial matching division was carried out for productive and service industries in different towns and streets, in order to provide reference for the transformation and upgrading of industrial structure in similar regions such as Liuhe District and even the Yangtze River Delta region.