The DC/DC converter provides stable power voltage and current for systems such as computer, communication, and telemetry and remote control systems. The power management chip is the core control unit of the power system. The radiation effect induced by various types of electromagnetic radiation in space imposes challenges to the performance indicators, reliability, and service life of electronic equipment. With the increasing development of deep space exploration and commercial aerospace systems, the demand for a high performance of power chip resistance is increasing. The pulse width modulation (PWM) controller proposed in this article is based on dual-crystal self-aimed at silicon-on-insulator (SOI) complementary bipolar techniques and adopts a various anti-radiation designs to achieve a good radical resistance. Specifically, the anti-total dosage ability of the chip is greater than 1 000 Gy (Si), and the ability to inject neutrons is greater than 2×10¹³ n/cm². The chip has been applied to multiple projects, thus playing an important role in improving the anti-radiation capacity of power systems.