With the rapid development of information technology, new media technology has been widely applied in the field of education. By observing the application and effect of new media technology in ophthalmology nursing teaching of the optometry nursing major, the results showed that the application of new media technology effectively improved teaching quality, enhanced students' interest in learning and self-learning ability, and promoted interaction between teachers and students. At the same time, there were also some problems in the application of new media technology. In order to further improve the quality and effect of teaching, it was proposed to strengthen the construction of teaching resources, enhance the teachers' information technology teaching ability and optimize the teaching design.