A method of computer-generated hologram for the three-dimensional (3D) object based on integral imaging is proposed. The method uses the micro-lens array to form an array of the elemental images and gains an array of the orthographic projection images through pixel extraction. According to the principle of the 3D central slice theorem, a series of the two-dimensional (2D) Fourier spectra of orthographic view images are put in the corresponding 3D Fourier space, and the intersections are extracted and superimposed to obtain the distribution of the 3D object′s spectra in the later focal plane of the lens. The distribution of Fresnel diffraction on the specific propagation distance is calculated, and the Fresnel computer-generated hologram is obtained by using holographic encoding method. The numerical reconstruction images of the Fresnel holograms at different distances show that the method is feasible. The method can obtain the hologram of real-existing 3D objects using the 3D Fourier spectrum with regular incoherent illumination. It reduces the complexity of the system, and the algorithm is simpler.