Considering the poor precision performance and high cost of the current wireless positioning algorithms, and combined with light emitting diode (LED) lights based visible light communication (VLC) system, a new wireless positioning algorithm based on camera calibration and with high precision is proposed, in vew of camera distortion effect, non- isotropic, assembly deviation on captured pictures. This algorithm could calculate the receiver′ s position, as well as its posture, with the position relationship to the LEDs, and LED position generated through the VLC system, and improve the anti- interference performance of VLC system through tracking and pointing. Experimental results show that this algorithm could achieve a positioning precision of a centimeter level, and generate relatively accurate posture information less than 5°. In addition, the bit error rate of the VLC with tracking and pointing performs two orders of magnitude better than the one with merely tracking, and improves the anti-interference capability and stability of the VLC system.