Based on the current situation of education and talents of optometry related majors in Jinling institute of technology, through the analysis of the current situation of optometry open educational resources and learning difficulties, combined with the basic theories of deep learning and research-based learning, a five step project or problem base learning(P&PBL) guided deep learning method was constructed, to explore a practical way and method of research-based learning of optometry based on deep learning and opened education resources. This method is conducive to enhance students' learning experience, improve learning efficiency, and improve their ability of holistic thinking, critical thinking and divergent thinking.