The Fe-based coatings with different compositions are produced on 45# steel by laser cladding technology, and the structure and property are analyzed. The results show that the cross section is composed of cladding coating, heat affected zone and the matrix after laser treatment, and the interface between cladding coating and the matrix is metallurgical bonding. The laser cladding coating is composed of columnar crystal, a little columnar crystal and fine dendrite, fine dendrite and carbides of type M23C6 from the bottom to surface. X-ray diffration results show that the content of austenite decreases and the content of martensite increases with the increment of B4C and Ti, while the microhardness and corrosion resistance are improved. However, when the Ti content reaches 4.5%, the structure changes obviously. Which is composed of a little cellular dendrite, fine dendrite and dendrite with plum blossom shape from the bottom to surface, and the hardness and corrosion resistance are best.