By introducing lanthanum oxide (La2O3) into the base composition of Mini LED backlight substrate glass, the effects of La2O3/Na2O, La2O3/CaO and La2O3/B2O3 on the thermal expansion coefficient and thermal conductivity coefficient of glass were investigated. The results indicate that the thermal expansion coefficient and thermal conductivity of the glass decrease with the increase of La2O3/Na2O. As the La2O3/CaO ratio increases, the thermal expansion coefficient of glass fluctuates within the range of (9.3~9.5)×10-6/℃, while the thermal conductivity shows a downward trend. With the increase of La2O3/B2O3, the thermal expansion coefficient of the glass decreases and the thermal conductivity increases.