Aiming at having large error in the linear nonuniformity correction method of Infrared Focal Plane Arrays (IRFPA) and complexity algorithm of nonlinear nonuniformity correction which limits its application in actual project,a new nonlinear nonuniformity correction method,which is easy to realize real-time correction and has higher precision,is proposed.Based on principle of new method,the mathematical model is established.At last,experimental results are given out.The results show that it has higher correction precision,less parameters needed to store and easy to implement real-time correction by hardware circuit.