The mixture design is a very effective method to solve formulation problems in the design of experiment. With the aid of JMP software, the best formulations of cover glass for electronic glass industry under the certain constraints can be obtained by using this optimal design method for mixed materials. The experimental results show this design method can establish an effective model based on fewer experimental expectation, propose the best experimental scheme and predict the optimal results. It is proved that the formulas proposed by the model have satisfactorily achieved the anticipated goal after practical experiment.