Since the perceived brightness of human visual system is nonlinear with the actual displayed brightness of the display, gamma correction for the video data of the display is required to adapt the display brightness to the needs of the human eye. This paper presents a gamma correction method for a silicon-based OLED micro-display. Firstly, based on the gamma characteristics of the human visual system, the basic principles of gamma correction are analyzed. Then, the bit width extension for the input video data is proposed to achieve the nonlinear output, and the gamma correction is implemented based on look-up table and segment-adjustable linear difference algorithm. Finally, the correction parameters are adjusted according to the actual XGA039 chip’s illumination. The experimental results show that the maximum luminance of the XGA039 chip is 20 000 cd/m2, and better display effect is obtained when the gamma value is 2.2 and the adjustable non-uniform segmentation is used. The proposed gamma correction method can significantly improve the display quality, and has certain advantages in accuracy and implementation area compared with the conventional methods.