Idiopathic retinal vasculitis aneurvsms and neuroretinitis (IRVAN) is a rare syndrome. The treatment is difficult and the natural prognosis is poor. We herein report a case of 55 years old and female patient. Her chief complaints were the vision loss of both eyes for more than 2 years and the visual distortion of right eye for about 50 days. A large number of retinal hard exudates could been seen in both retinas, and retinal vasculitis aneurvsms could been determined in the superior temporal of right eye and upon the optic disk of left eye. And epiretinal membrane could been seen around the macular area of the right eye. The main diagnosis of the patient is idiopathic retinal vasculitis aneurvsms and neuroretinitis (IRVAN) syndrome. Local laser photocoagulation therapy was been taken for the perfusion-free area. After the laser treatment, the patient's visual acuity was improved, macular edema and retinal hard exudate were reduced. After nearly 2 years of follow-up, the patient's condition was stable. Local laser photocoagulation therapy is an effective means for the patients with IRVAN syndrome.