The optical absorption of exogenous contrast agents in conventional photoacoustic imaging is mainly concentrated in the visible region and the traditional near infrared region (NIR, 750~900 nm). The development of near-infrared-II (NIR-II, 1 000~1 700 nm) nanoprobes with higher optical tissue penetration depth is of great significance for photoacoustic imaging of deep tissue in vivo. In this paper, semiconductor single-walled carbon nanotubes with optical absorption peaks of about 1 000 nm were selected as the exogenous contrast agent for near-infrared-Ⅱphotoacoustic imaging. The strong photoacoustic effect was tested under near-infrared-Ⅱlaser excitation. Furthermore, the deep photoacoustic imaging of the phantom tissue was obtained by embedding the nanomaterial in different depths of the tissue-mimic phantom. The imaging depth can reach 1.5 cm. Experimental results show that semiconductor single-walled carbon nanotubes (SWCNTs) with near-infrared-Ⅱ optical absorption have great potential in photoacoustic imaging of deep tissues in vivo.