Journal of Innovative Optical Health Sciences, Volume. 18, Issue 4, 2530006(2025)

End-to-end algorithm research in PACT — from signal processing to reconstruction solution to image processing: A review

JinJin Cheng1,2, Shuilin Wang1,3, Shirui Dong1, Yang Wang1, Xuyu Fu1, Jichao Zhang1,3, Wenkai Li1, Siyu Chen1, Silue Zeng1,4, Yaguang Ren1, Xiaohui Ma5, Jinhai Liu3, Mingjian Sun2,6、*, Rongkang Gao1、**, and Chengbo Liu1、***
Author Affiliations
  • 1Research Center for Biomedical Optics and Molecular Imaging, Key Laboratory of Biomedical Imaging Science and Systems, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, P. R. China
  • 2China Department of Control Science and Engineering, Harbin Institute of Technology, Weihai, Shandong 264200, P. R. China
  • 3College of Information Science and Engineering, Northeastern University, Shenyang 110004, P. R. China
  • 4Department of Hepatobiliary Surgery I, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, P. R. China
  • 5The First Medical Center of Chinese PLA General Hospital, The Department of Vascular and Endovascular Surgery, Beijing, P. R. China
  • 6Department of Control Science and Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150001, P. R. China
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    Photoacoustic computed tomography (PACT) is an innovative biomedical imaging technique that has gained significant application in the field of biomedicine due to its ability to visualize optical contrast with high resolution and deep tissue penetration. However, the inherent challenges associated with photoacoustic signal excitation, propagation and detection often result in suboptimal image quality. To overcome these limitations, researchers have developed various advanced algorithms that span the entire image reconstruction pipeline. This review paper aims to present a detailed analysis of the latest advancements in PACT algorithms and synthesize these algorithms into a coherent framework. We provide tripartite analysis — from signal processing to reconstruction solution to image processing, covering a spectrum of techniques. The principles and methodologies, as well as their applicability and limitations, are thoroughly discussed. The primary objective of this study is to provide a thorough review of advanced algorithms applicable to PACT, offering both theoretical foundations and practical guidance for enhancing the imaging effect of PACT.

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    JinJin Cheng, Shuilin Wang, Shirui Dong, Yang Wang, Xuyu Fu, Jichao Zhang, Wenkai Li, Siyu Chen, Silue Zeng, Yaguang Ren, Xiaohui Ma, Jinhai Liu, Mingjian Sun, Rongkang Gao, Chengbo Liu. End-to-end algorithm research in PACT — from signal processing to reconstruction solution to image processing: A review[J]. Journal of Innovative Optical Health Sciences, 2025, 18(4): 2530006

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    Paper Information

    Category: Research Articles

    Received: Dec. 1, 2024

    Accepted: Dec. 29, 2024

    Published Online: Jun. 18, 2025

    The Author Email: Mingjian Sun (sunmingjian@hit.edu.cn), Rongkang Gao (rk.gao@siat.ac.cn), Chengbo Liu (cb.liu@siat.ac.cn)

    DOI:10.1142/S179354582530006X

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