With the rapid expansion of global trade, cold chain logistics becomes a critical component in ensuring the safety of food and pharmaceutical products. This study presents the development of a novel high-power deep ultraviolet light emitting diode (UVC-LED) disinfection technology aimed at addressing the survival of microorganisms and viruses, particularly the novel coronavirus (SARS-CoV-2) under prolonged low-temperature conditions. The research details the design and fabrication of a UVC-LED device based on aluminum-gallium-nitride (AlGaN) material. Additionally, ice layers with varying transparency are prepared by controlling water freezing rates, and the propagation characteristics of lightwaves through these ice layers are simulated using COMSOL software. Experimental results demonstrate the bactericidal efficacy of the light emitted by the UVC-LED device when penetrating ice and evaluate its capacity to inactivate SARS-CoV-2. The findings confirm the efficiency and reliability of high-power UVC-LED devices for disinfection in cold chain logistics. This study provides a scientific basis for the application of UVC-LED devices in cold chain disinfection and contributes to the development and optimization of future technologies.