Wander and spreading of polarized and partially coherent laser propagation on slant path in turbulence atmospheric are studied by using the first and second moment of optical field as evaluation parameters. According to extended Huygens-Fresnel principle, the elliptically polarized and partially coherent laser beam is taken as a study object. The analytical expressions for barycentric coordinate, spreading radius and spreading angle of beam on the slant path are derived, and the effects of the phase difference between two orthogonal components of polarization beam, direction angle, wavelength, initial waist radius and receiver height on wander and spreading of laser beam are analyzed. Results show that the wander effect increases at first, and then decreases with the phase difference between two orthogonal components of polarization beam increasing under the certain slant path transmission distance and receiver height. The effect of wander and spreading of beam decreases with the increase of receiver height under the certain slant path transmission distance.