Nd:YAG pulse laser is used to weld 0.1 mm+0.8 mm+0.1 mm double-sided ultra-thin stainless steel clad plate with high chromium-nickel alloy powders as filling materials. The microstructure, tensile strength, micro hardness of welded joints, and corrosion resistance of welding surface are studied. The results show that it has good welding appearance, little deformation, non-defect, and the connecting among weld metal, stainless steel layer and the base are fine; weld center is small equiaxed of the grain orientation without regularity, and other regional is columnar crystal, barely seeing the heat affected zone (HAZ), and weld microstructure is austenite+a little ferritic+a little martensite; tensile strength of welded joint has reached 92% of the base metal, and elongatiion is 25% of base metal; the micro hardness of weld zone has been significantly improved than the base metal; electrochemical corrosion of the weld surface is similar to the composite layer of the base metal.