The theory and related mechanism of asymmetric gamma tuning effect on image sticking of display panels are analyzed. The effect of asymmetric gamma tuning on image sticking is verified by evaluation of the actual panel. The actual verification results show that, the area image sticking caused by the DC residual is significantly improved by adjusting the different gray scale voltage centers to compensate for the difference of the kickback voltage compared with the gray scale 127. The levels of short, medium and long-term image sticking decreased by about 2, 0.8 and 0.6 respectively. The results fully show that the area image sticking caused by DC residual can be effectively improved by the asymmetric Gamma adjustment method, which can be applied to actual products design to reduce the risk and grade of area image sticking.