Supercontinuum generation using femtosecond pulse in a nonlinear dispersion flattened photonic crystal fiber is experimentally demonstrated. The photonic crystal fiber with a nonlinearity of about 11 W-1·km-1 is characterized by flattened chromatic dispersion. The chromatic dispersion varies less than 1.2 ps/(nm·km) between 1500 nm and 1650 nm. By injecting 120 fs optical pulses into an 40 m-long dispersion-flattened photonic crystal fiber, the supercontinuum with a broadened spectrum of 480 nm (at 20 dB level) is achieved, it has important applications, such as supercontinuum source and optical wavelength conversion.